The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells

Histones modulate gene expression by chromatin compaction, regulating numerous processes such as differentiation. However, the mechanisms underlying histone degradation remain elusive. Human embryonic stem cells (hESCs) have a unique chromatin architecture characterized by low levels of trimethylate...

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Detalles Bibliográficos
Autores principales: Fatima, Azra, Irmak, Dilber, Noormohammadi, Alireza, Rinschen, Markus M., Das, Aniruddha, Leidecker, Orsolya, Schindler, Christina, Sánchez-Gaya, Víctor, Wagle, Prerana, Pokrzywa, Wojciech, Hoppe, Thorsten, Rada-Iglesias, Alvaro, Vilchez, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248108/
https://www.ncbi.nlm.nih.gov/pubmed/32451438
http://dx.doi.org/10.1038/s42003-020-0984-3

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