Cargando…

Dihydroquercetin Activates AMPK/Nrf2/HO-1 Signaling in Macrophages and Attenuates Inflammation in LPS-Induced Endotoxemic Mice

Dihydroquercetin (DHQ) is a flavonoid compound known for its anti-oxidant effects. Oxidative stress plays a dominant role in regulating the pathways associated with systemic inflammatory immune activation during endotoxemia. Whether and how DHQ regulates inflammatory responses in endotoxemia remains...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lei, Liming, Chai, Yunfei, Lin, Haoming, Chen, Chunbo, Zhao, Mingyi, Xiong, Weiping, Zhuang, Jian, Fan, Xiaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248193/ https://www.ncbi.nlm.nih.gov/pubmed/32508636 http://dx.doi.org/10.3389/fphar.2020.00662

Ejemplares similares

Dihydroquercetin ameliorates LPS-induced neuroinflammation and memory deficit
por: Alam, Qadir, et al.
Publicado: (2022)

Effect of Dihydroquercetin on Energy Metabolism in LPS-Induced Inflammatory Mice
por: Yu, Xiaoying, et al.
Publicado: (2022)

Bioavailability and Safety of Dihydroquercetin (Review)
por: Orlova, S. V., et al.
Publicado: (2022)

Dihydroquercetin Attenuates Silica-Induced Pulmonary Fibrosis by Inhibiting Ferroptosis Signaling Pathway
por: Yuan, Leyong, et al.
Publicado: (2022)

Research Progress of Dihydroquercetin in the Treatment of Skin Diseases
por: Liu, Ziyang, et al.
Publicado: (2023)

Tetralone derivatives are MIF tautomerase inhibitors and attenuate macrophage activation and amplify the hypothermic response in endotoxemic mice
por: Garai, János, et al.
Publicado: (2021)

Skin Penetration Enhancement by Natural Oils for Dihydroquercetin Delivery
por: Čižinauskas, Vytis, et al.
Publicado: (2017)

Solubility Enhancement of Dihydroquercetin via “Green” Phase Modification
por: Terekhov, Roman P., et al.
Publicado: (2022)

Engineering Saccharomyces cerevisiae for the production of dihydroquercetin from naringenin
por: Yu, Shiqin, et al.
Publicado: (2022)

Panaxydol attenuates ferroptosis against LPS-induced acute lung injury in mice by Keap1-Nrf2/HO-1 pathway
por: Li, Jiucui, et al.
Publicado: (2021)

Penfluroidol Attenuates the Imbalance of the Inflammatory Response by Repressing the Activation of the NLRP3 Inflammasome and Reduces Oxidative Stress via the Nrf2/HO-1 Signaling Pathway in LPS-Induced Macrophages
por: Li, Qiulin, et al.
Publicado: (2023)

Milrinone Attenuates Arteriolar Vasoconstriction and Capillary Perfusion Deficits on Endotoxemic Hamsters
por: de Miranda, Marcos Lopes, et al.
Publicado: (2015)

Sargachromenol Purified from Sargassum horneri Inhibits Inflammatory Responses via Activation of Nrf2/HO-1 Signaling in LPS-Stimulated Macrophages
por: Han, Eui-Jeong, et al.
Publicado: (2021)

Research on Characteristics, Antioxidant and Antitumor Activities of Dihydroquercetin and Its Complexes
por: Zhang, Yan, et al.
Publicado: (2017)

Comparative Study of Wound-Healing Activity of Dihydroquercetin Pseudopolymorphic Modifications
por: Terekhov, R. P., et al.
Publicado: (2021)

Exploring the genes involved in biosynthesis of dihydroquercetin and dihydromyricetin in Ampelopsis grossedentata
por: Yu, Zheng-Wen, et al.
Publicado: (2021)

Unraveling the Antioxidant Activity of 2R,3R-dihydroquercetin
por: Xu, Yaping, et al.
Publicado: (2023)

Opioids Alleviate Oxidative Stress via the Nrf2/HO-1 Pathway in LPS-Stimulated Microglia
por: Shivling Mali, Akash, et al.
Publicado: (2023)

Nattokinase Attenuates Retinal Neovascularization Via Modulation of Nrf2/HO-1 and Glial Activation
por: Huang, Zijing, et al.
Publicado: (2021)

Moracin attenuates LPS-induced inflammation in nucleus pulposus cells via Nrf2/HO-1 and NF-κB/TGF-β pathway
por: Gu, Ronghe, et al.
Publicado: (2019)

Saussureae Radix Attenuates Neuroinflammation in LPS-Stimulated Mouse BV2 Microglia via HO-1/Nrf-2 Induction and Inflammatory Pathway Inhibition
por: Oh, You-Chang, et al.
Publicado: (2021)

Etomidate attenuates hyperoxia-induced acute lung injury in mice by modulating the Nrf2/HO-1 signaling pathway
por: Jia, Liming, et al.
Publicado: (2021)

Daeshiho-tang attenuates inflammatory response and oxidative stress in LPS-stimulated macrophages by regulating TLR4/MyD88, NF-κB, MAPK, and Nrf2/HO-1 pathways
por: Oh, Yong Jin, et al.
Publicado: (2023)

LPS Down-Regulates Specificity Protein 1 Activity by Activating NF-κB Pathway in Endotoxemic Mice
por: Ye, Xiaobing, et al.
Publicado: (2015)

New Insights into the Nrf-2/HO-1 Signaling Axis and Its Application in Pediatric Respiratory Diseases
por: Zhang, Xueyan, et al.
Publicado: (2019)

Betulin exhibits anti-inflammatory activity in LPS-stimulated macrophages and endotoxin-shocked mice through an AMPK/AKT/Nrf2-dependent mechanism
por: Ci, Xinxin, et al.
Publicado: (2017)

Toxicity of Silver Nanoparticles Supported by Surface-Modified Zirconium Dioxide with Dihydroquercetin
por: Sredojević, Dušan, et al.
Publicado: (2022)

Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway
por: Lou, Lejing, et al.
Publicado: (2023)

Activated AMPK boosts the Nrf2/HO-1 signaling axis—A role for the unfolded protein response
por: Zimmermann, Kristin, et al.
Publicado: (2015)

Aucubin inhibited lipid accumulation and oxidative stress via Nrf2/HO‐1 and AMPK signalling pathways
por: Shen, Bingyu, et al.
Publicado: (2019)

1-Nitropyrene Induced Reactive Oxygen Species–Mediated Apoptosis in Macrophages through AIF Nuclear Translocation and AMPK/Nrf-2/HO-1 Pathway Activation
por: Su, Chun-Hung, et al.
Publicado: (2021)

Danaparoid sodium attenuates the increase in inflammatory cytokines and preserves organ function in endotoxemic rats
por: Iba, Toshiaki, et al.
Publicado: (2008)

Dexmedetomidine ameliorates muscle wasting and attenuates the alteration of hypothalamic neuropeptides and inflammation in endotoxemic rats
por: Cheng, Minhua, et al.
Publicado: (2017)

AICAR inhibits NFκB DNA binding independently of AMPK to attenuate LPS-triggered inflammatory responses in human macrophages
por: Kirchner, Johannes, et al.
Publicado: (2018)

Effect of Apremilast on LPS-induced immunomodulation and inflammation via activation of Nrf2/HO-1 pathways in rat lungs
por: Al-Harbi, Naif O., et al.
Publicado: (2023)

Efficacy of glucosamine alendronate alone & in combination with dihydroquercetin for treatment of osteoporosis in animal model
por: Muraleva, Natalya A., et al.
Publicado: (2012)

The Nrf-2/HO-1 Signaling Axis: A Ray of Hope in Cardiovascular Diseases
por: Zhang, Xueyan, et al.
Publicado: (2020)

Dexmedetomidine Attenuates LPS-Induced Monocyte-Endothelial Adherence via Inhibiting Cx43/PKC-α/NOX2/ROS Signaling Pathway in Monocytes
por: Chai, Yunfei, et al.
Publicado: (2020)

Endothelin Receptor A Antagonism Attenuates Renal Medullary Blood Flow Impairment in Endotoxemic Pigs
por: Fenhammar, Johan, et al.
Publicado: (2011)

Tetrahydropyrimidines, ZL-5015 Alleviated Lipopolysaccharide (LPS)-Induced Acute Pneumonia in Rats by Activating the NRF-2/HO-1 Pathway
por: Sun, Wei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_cnjgbbdcs4pvs9rdgnkb5gndi9