Cargando…

Validation of a Double-Sandwich Enzyme-Linked Immunoassay for Pharmacokinetic Study of an rh-aFGF Hydrogel in Rat Skin and Serum

In this study, we validated a double-sandwich enzyme-linked immunosorbent assay (ELISA) to investigate the pharmacokinetics of a recombinant human acidic fibroblast growth factor (rh-aFGF) hydrogel in rat skin and serum. A total of 130 Sprague-Dawley rats were divided into a control group, rh-aFGF h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hui, Qi, Yang, Rongshuai, Lu, Chao, Bi, Jianing, Li, Lijia, Gong, Jianxiang, Zhang, Li, Jin, Zi, Li, Xiaokun, Wang, Xiaojie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248203/ https://www.ncbi.nlm.nih.gov/pubmed/32508643 http://dx.doi.org/10.3389/fphar.2020.00700

Ejemplares similares

Long-Term Toxicity Study of Topical Administration of a Highly-Stable rh-aFGF Carbomer 940 Hydrogel in a Rabbit Skin Wound Model
por: Zhang, Li, et al.
Publicado: (2020)

Hypoglycemic Efficacy of Rh-aFGF Variants in Treatment of Diabetes in ZDF Rats
por: Zhang, Li, et al.
Publicado: (2021)

KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats
por: Yang, Xuanxin, et al.
Publicado: (2020)

Repression of myogenic differentiation by aFGF, bFGF, and K-FGF is dependent on cellular heparan sulfate
Publicado: (1992)

Comparison of FGF1 (aFGF) Expression between the Dorsal Motor Nucleus of Vagus and the Hypoglossal Nucleus of Rat
por: Toyoda, Ken-ichiro, et al.
Publicado: (2006)

aFGF alleviates diabetic endothelial dysfunction by decreasing oxidative stress via Wnt/β-catenin-mediated upregulation of HXK2
por: Sun, Jia, et al.
Publicado: (2020)

Improving the protective effects of aFGF for peripheral nerve injury repair using sulfated chitooligosaccharides
por: Liu, Yanmei, et al.
Publicado: (2019)

Inhibition of endoplasmic reticulum stress is involved in the neuroprotective effect of aFGF in neonatal hypoxic-ischaemic brain injury
por: Hu, Yingying, et al.
Publicado: (2017)

FGF Family: From Drug Development to Clinical Application
por: Hui, Qi, et al.
Publicado: (2018)

Flotation Immunoassay: Masking the Signal from Free Reporters in Sandwich Immunoassays
por: Chen, Hui, et al.
Publicado: (2016)

The effect of ethanolic extract of Brazilian green propolis and artepillin C on aFGF-1, Eselectin, and CD40L secreted by human gingival fibroblasts
por: Kłósek, Małgorzata, et al.
Publicado: (2021)

Hypoxia Response Element-Directed Expression of aFGF in Neural Stem Cells Promotes the Recovery of Spinal Cord Injury and Attenuates SCI-Induced Apoptosis
por: Ying, Yibo, et al.
Publicado: (2021)

Development and Validation of an Ultrasensitive Procalcitonin Sandwich Immunoassay
por: Carcamo Yañez, Viviana A., et al.
Publicado: (2017)

Corrigendum: Hypoxia response element-directed expression of aFGF in neural stem cells promotes the recovery of spinal cord injury and attenuates SCI-induced apoptosis
por: Ying, Yibo, et al.
Publicado: (2022)

A Better Anti-Diabetic Recombinant Human Fibroblast Growth Factor 21 (rhFGF21) Modified with Polyethylene Glycol
por: Huang, Zhifeng, et al.
Publicado: (2011)

Efficient treatment of Parkinson’s disease using ultrasonography-guided rhFGF20 proteoliposomes
por: Niu, Jianlou, et al.
Publicado: (2018)

aFGF Targeted Mediated by Novel Nanoparticles-Microbubble Complex Combined With Ultrasound-Targeted Microbubble Destruction attenuates Doxorubicin-Induced Heart Failure via Anti-Apoptosis and Promoting Cardiac Angiogenesis
por: Zhou, Nan-Qian, et al.
Publicado: (2021)

Upconversion Cross‐Correlation Spectroscopy of a Sandwich Immunoassay
por: Lahtinen, Satu, et al.
Publicado: (2018)

Amperometric Biosensor for Quantitative Measurement Using Sandwich Immunoassays
por: Pedersen, Thor, et al.
Publicado: (2023)

Potent long-acting rhFGF21 analog for treatment of diabetic nephropathy in db/db and DIO mice
por: Zhao, Longwei, et al.
Publicado: (2017)

The FGF metabolic axis
por: Li, Xiaokun
Publicado: (2019)

Donut-like MOFs of copper/nicotinic acid and composite hydrogels with superior bioactivity for rh-bFGF delivering and skin wound healing
por: Wang, Tian-Long, et al.
Publicado: (2021)

Development of a New Chemiluminescent Enzyme Immunoassay Using a Two-Step Sandwich Method for Measuring Aldosterone Concentrations
por: Ozeki, Yoshinori, et al.
Publicado: (2021)

A miniaturized sandwich immunoassay platform for the detection of protein-protein interactions
por: Liu, Qiongming, et al.
Publicado: (2010)

Effects of High-Biotin Sample Interference on Antibody Concentrations in Sandwich Immunoassays
por: Balieiro Neto, Geraldo, et al.
Publicado: (2023)

Oriented Immobilization and Quantitative Analysis Simultaneously Realized in Sandwich Immunoassay via His-Tagged Nanobody
por: Xu, Li, et al.
Publicado: (2019)

Hydrogel Delivery Device for the In Vitro and In Vivo Sustained Release of Active rhGALNS Enzyme
por: Flanagan, Michael, et al.
Publicado: (2023)

Electrochemical Enzyme Immunoassay
por: Halsall, H. Brian, et al.
Publicado: (1988)

Oil body bound oleosin-rhFGF9 fusion protein expressed in safflower (Carthamus tinctorius L.) stimulates hair growth and wound healing in mice
por: Cai, Jingbo, et al.
Publicado: (2018)

Sandwich Immunoassays of Multicomponent Subtrace Pathogenic DNA Based on Magnetic Fluorescent Encoded Nanoparticles
por: Liu, Yaxu, et al.
Publicado: (2016)

Facilitating the Validation of Novel Protein Biomarkers for Dementia: An Optimal Workflow for the Development of Sandwich Immunoassays
por: del Campo, Marta, et al.
Publicado: (2015)

Nanobody-Based Sandwich Immunoassay for Pathogenic Escherichia coli F17 Strain Detection
por: Dhehibi, Asma, et al.
Publicado: (2023)

Comparison of Chemiluminescence Enzyme Immunoassay (Cl-ELISA) with Colorimetric Enzyme Immunoassay (Co-ELISA) for Imidacloprid Detection in Vegetables
por: Zhai, Rongqi, et al.
Publicado: (2023)

Oil Body-Bound Oleosin-rhFGF-10: A Novel Drug Delivery System that Improves Skin Penetration to Accelerate Wound Healing and Hair Growth in Mice
por: Li, Wenqing, et al.
Publicado: (2017)

Combined treatment with ultrasound-targeted microbubble destruction technique and NM-aFGF-loaded PEG-nanoliposomes protects against diabetic cardiomyopathy-induced oxidative stress by activating the AKT/GSK-3β1/Nrf-2 pathway
por: Zhang, Ming, et al.
Publicado: (2020)

Principles of the Design of Enzyme Immunoassays
por: KURSTAK, EDOUARD
Publicado: (1986)

Enzyme Immunoassays for Infectious Diseases
por: KURSTAK, EDOUARD
Publicado: (1986)

rhFGF-21 accelerates corneal epithelial wound healing through the attenuation of oxidative stress and inflammatory mediators in diabetic mice
por: Li, Le, et al.
Publicado: (2023)

Enhancement of Fluorescence-Based Sandwich Immunoassay Using Multilayered Microplates Modified with Plasma-Polymerized Films
por: Yano, Kazuyoshi, et al.
Publicado: (2016)

Highly sensitive sandwich immunoassay and immunochromatographic test for the detection of Clostridial epsilon toxin in complex matrices
por: Féraudet-Tarisse, Cécile, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_jj64205l7a5js0i4iu59kasp0f