Cargando…
Accumulation of TB-Active Compounds in Murine Organs Relevant to Infection by Mycobacterium tuberculosis
Tuberculosis (TB), the leading cause of death due to an infectious agent, requires prolonged and costly drug treatments. With the rise in incidence of MDR and XDR TB, newer more efficacious treatments which are better able to permeate into the deeper recesses of the human lung where bacteria reside...
Autores principales: | Tanner, Lloyd, Haynes, Richard K., Wiesner, Lubbe |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248252/ https://www.ncbi.nlm.nih.gov/pubmed/32508649 http://dx.doi.org/10.3389/fphar.2020.00724 |
Ejemplares similares
-
An in vitro ADME and in vivo Pharmacokinetic Study of Novel TB-Active Decoquinate Derivatives
por: Tanner, Lloyd, et al.
Publicado: (2019) -
Intracellular Accumulation of Novel and Clinically Used TB Drugs Potentiates Intracellular Synergy
por: Tanner, Lloyd, et al.
Publicado: (2021) -
The evaluation of ADME and pharmacokinetic properties of decoquinate derivatives for the treatment of malaria
por: Watson, Daniel J., et al.
Publicado: (2022) -
Toward New Transmission-Blocking Combination Therapies: Pharmacokinetics of 10-Amino-Artemisinins and 11-Aza-Artemisinin and Comparison with Dihydroartemisinin and Artemether
por: Watson, Daniel J., et al.
Publicado: (2021) -
HIV-1 Coinfection Does Not Reduce Exposure to Rifampin, Isoniazid, and Pyrazinamide in South African Tuberculosis Outpatients
por: Rockwood, Neesha, et al.
Publicado: (2016)