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Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir

Following the first case of Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-Cov-2), in Wuhan, China, in December 2019, it has spread worldwide. An outbreak in Japan occurred on a cruise ship, and this was followed by community-acquired COVID-19. H...

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Autores principales: Wada, Tatsuhiko, Shimode, Kosuke, Hoshiyama, Takayuki, Takayama, Yoko, Yamaoka, Kunihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248319/
https://www.ncbi.nlm.nih.gov/pubmed/32574332
http://dx.doi.org/10.3389/fmed.2020.00241
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author Wada, Tatsuhiko
Shimode, Kosuke
Hoshiyama, Takayuki
Takayama, Yoko
Yamaoka, Kunihiro
author_facet Wada, Tatsuhiko
Shimode, Kosuke
Hoshiyama, Takayuki
Takayama, Yoko
Yamaoka, Kunihiro
author_sort Wada, Tatsuhiko
collection PubMed
description Following the first case of Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-Cov-2), in Wuhan, China, in December 2019, it has spread worldwide. An outbreak in Japan occurred on a cruise ship, and this was followed by community-acquired COVID-19. Herein, we report three cases of COVID-19 that presented pneumonia following admission to Kitasato University Hospital. Patients were admitted based on the positive result of real-time reverse transcriptase–polymerase chain reaction (RT-PCR) tests for COVID-19 nucleic acid. All patients were diagnosed as suffering from non-severe COVID-19 pneumonia and were successfully treated with Lopinavir/Ritonavir (LPV/r). LPV/r could be an option for treating non-severe COVID-19 pneumonia in general and even in elderly patients.
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spelling pubmed-72483192020-06-05 Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir Wada, Tatsuhiko Shimode, Kosuke Hoshiyama, Takayuki Takayama, Yoko Yamaoka, Kunihiro Front Med (Lausanne) Medicine Following the first case of Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-Cov-2), in Wuhan, China, in December 2019, it has spread worldwide. An outbreak in Japan occurred on a cruise ship, and this was followed by community-acquired COVID-19. Herein, we report three cases of COVID-19 that presented pneumonia following admission to Kitasato University Hospital. Patients were admitted based on the positive result of real-time reverse transcriptase–polymerase chain reaction (RT-PCR) tests for COVID-19 nucleic acid. All patients were diagnosed as suffering from non-severe COVID-19 pneumonia and were successfully treated with Lopinavir/Ritonavir (LPV/r). LPV/r could be an option for treating non-severe COVID-19 pneumonia in general and even in elderly patients. Frontiers Media S.A. 2020-05-19 /pmc/articles/PMC7248319/ /pubmed/32574332 http://dx.doi.org/10.3389/fmed.2020.00241 Text en Copyright © 2020 Wada, Shimode, Hoshiyama, Takayama and Yamaoka. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Wada, Tatsuhiko
Shimode, Kosuke
Hoshiyama, Takayuki
Takayama, Yoko
Yamaoka, Kunihiro
Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir
title Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir
title_full Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir
title_fullStr Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir
title_full_unstemmed Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir
title_short Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir
title_sort three novel covid-19 pneumonia cases successfully treated with lopinavir/ritonavir
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248319/
https://www.ncbi.nlm.nih.gov/pubmed/32574332
http://dx.doi.org/10.3389/fmed.2020.00241
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