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Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir
Following the first case of Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-Cov-2), in Wuhan, China, in December 2019, it has spread worldwide. An outbreak in Japan occurred on a cruise ship, and this was followed by community-acquired COVID-19. H...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248319/ https://www.ncbi.nlm.nih.gov/pubmed/32574332 http://dx.doi.org/10.3389/fmed.2020.00241 |
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author | Wada, Tatsuhiko Shimode, Kosuke Hoshiyama, Takayuki Takayama, Yoko Yamaoka, Kunihiro |
author_facet | Wada, Tatsuhiko Shimode, Kosuke Hoshiyama, Takayuki Takayama, Yoko Yamaoka, Kunihiro |
author_sort | Wada, Tatsuhiko |
collection | PubMed |
description | Following the first case of Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-Cov-2), in Wuhan, China, in December 2019, it has spread worldwide. An outbreak in Japan occurred on a cruise ship, and this was followed by community-acquired COVID-19. Herein, we report three cases of COVID-19 that presented pneumonia following admission to Kitasato University Hospital. Patients were admitted based on the positive result of real-time reverse transcriptase–polymerase chain reaction (RT-PCR) tests for COVID-19 nucleic acid. All patients were diagnosed as suffering from non-severe COVID-19 pneumonia and were successfully treated with Lopinavir/Ritonavir (LPV/r). LPV/r could be an option for treating non-severe COVID-19 pneumonia in general and even in elderly patients. |
format | Online Article Text |
id | pubmed-7248319 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-72483192020-06-05 Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir Wada, Tatsuhiko Shimode, Kosuke Hoshiyama, Takayuki Takayama, Yoko Yamaoka, Kunihiro Front Med (Lausanne) Medicine Following the first case of Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-Cov-2), in Wuhan, China, in December 2019, it has spread worldwide. An outbreak in Japan occurred on a cruise ship, and this was followed by community-acquired COVID-19. Herein, we report three cases of COVID-19 that presented pneumonia following admission to Kitasato University Hospital. Patients were admitted based on the positive result of real-time reverse transcriptase–polymerase chain reaction (RT-PCR) tests for COVID-19 nucleic acid. All patients were diagnosed as suffering from non-severe COVID-19 pneumonia and were successfully treated with Lopinavir/Ritonavir (LPV/r). LPV/r could be an option for treating non-severe COVID-19 pneumonia in general and even in elderly patients. Frontiers Media S.A. 2020-05-19 /pmc/articles/PMC7248319/ /pubmed/32574332 http://dx.doi.org/10.3389/fmed.2020.00241 Text en Copyright © 2020 Wada, Shimode, Hoshiyama, Takayama and Yamaoka. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Wada, Tatsuhiko Shimode, Kosuke Hoshiyama, Takayuki Takayama, Yoko Yamaoka, Kunihiro Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir |
title | Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir |
title_full | Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir |
title_fullStr | Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir |
title_full_unstemmed | Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir |
title_short | Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir |
title_sort | three novel covid-19 pneumonia cases successfully treated with lopinavir/ritonavir |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248319/ https://www.ncbi.nlm.nih.gov/pubmed/32574332 http://dx.doi.org/10.3389/fmed.2020.00241 |
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