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Locally Controlled Release of Methotrexate and Alendronate by Thermo-Sensitive Hydrogels for Synergistic Inhibition of Osteosarcoma Progression
Osteosarcoma (OS) is a serious primary bone malignant tumor that can easily affect children and adolescents. Chemotherapy is one of the important and feasible clinical treatment strategies for the treatment of OS at present, which is severely limited due to insufficient retention time, poor penetrat...
Autores principales: | Shan, Hongli, Li, Ke, Zhao, Duoyi, Chi, Changliang, Tan, Qinyuan, Wang, Xiaoqing, Yu, Jinhai, Piao, Meihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248331/ https://www.ncbi.nlm.nih.gov/pubmed/32508628 http://dx.doi.org/10.3389/fphar.2020.00573 |
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