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Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset
Bronchopulmonary dysplasia (BPD) is a severe pulmonary complication of prematurity and is associated with significant morbidity or death. Early use of systemic corticosteroids may alter the trajectory of the disease and improve outcomes. A BPD Outcomes estimator, developed by the NICHD using a large...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248447/ https://www.ncbi.nlm.nih.gov/pubmed/32478148 http://dx.doi.org/10.1016/j.dib.2020.105674 |
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author | Vesoulis, Zachary A. McPherson, Christopher C. Whitehead, Halana V. |
author_facet | Vesoulis, Zachary A. McPherson, Christopher C. Whitehead, Halana V. |
author_sort | Vesoulis, Zachary A. |
collection | PubMed |
description | Bronchopulmonary dysplasia (BPD) is a severe pulmonary complication of prematurity and is associated with significant morbidity or death. Early use of systemic corticosteroids may alter the trajectory of the disease and improve outcomes. A BPD Outcomes estimator, developed by the NICHD using a large population dataset, can be used to calculate individual risk. Risk above a certain threshold may indicate that the benefits of corticosteroids outweigh the risks. Empiric analysis of this calculator by systematic entry of synthetic patient information reveals a marked racial disparity; black infants have lower risk of moderate/severe BPD due to a higher risk of death despite equivalent severity of illness. Interpretation and analysis of this finding can be found in “The challenge of risk stratification of preterm infants in the setting of competing and disparate healthcare outcomes” [1]. In this report, we provide the underlying data used in this analysis. Calculator output for 108 example patients, systematically varied by sex, birthweight, race, type of ventilator, and fraction of inspired oxygen (FiO(2)), is reported. |
format | Online Article Text |
id | pubmed-7248447 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-72484472020-05-29 Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset Vesoulis, Zachary A. McPherson, Christopher C. Whitehead, Halana V. Data Brief Medicine and Dentistry Bronchopulmonary dysplasia (BPD) is a severe pulmonary complication of prematurity and is associated with significant morbidity or death. Early use of systemic corticosteroids may alter the trajectory of the disease and improve outcomes. A BPD Outcomes estimator, developed by the NICHD using a large population dataset, can be used to calculate individual risk. Risk above a certain threshold may indicate that the benefits of corticosteroids outweigh the risks. Empiric analysis of this calculator by systematic entry of synthetic patient information reveals a marked racial disparity; black infants have lower risk of moderate/severe BPD due to a higher risk of death despite equivalent severity of illness. Interpretation and analysis of this finding can be found in “The challenge of risk stratification of preterm infants in the setting of competing and disparate healthcare outcomes” [1]. In this report, we provide the underlying data used in this analysis. Calculator output for 108 example patients, systematically varied by sex, birthweight, race, type of ventilator, and fraction of inspired oxygen (FiO(2)), is reported. Elsevier 2020-05-11 /pmc/articles/PMC7248447/ /pubmed/32478148 http://dx.doi.org/10.1016/j.dib.2020.105674 Text en © 2020 The Authors. Published by Elsevier Inc. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Medicine and Dentistry Vesoulis, Zachary A. McPherson, Christopher C. Whitehead, Halana V. Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset |
title | Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset |
title_full | Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset |
title_fullStr | Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset |
title_full_unstemmed | Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset |
title_short | Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset |
title_sort | racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset |
topic | Medicine and Dentistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248447/ https://www.ncbi.nlm.nih.gov/pubmed/32478148 http://dx.doi.org/10.1016/j.dib.2020.105674 |
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