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Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset

Bronchopulmonary dysplasia (BPD) is a severe pulmonary complication of prematurity and is associated with significant morbidity or death. Early use of systemic corticosteroids may alter the trajectory of the disease and improve outcomes. A BPD Outcomes estimator, developed by the NICHD using a large...

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Autores principales: Vesoulis, Zachary A., McPherson, Christopher C., Whitehead, Halana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248447/
https://www.ncbi.nlm.nih.gov/pubmed/32478148
http://dx.doi.org/10.1016/j.dib.2020.105674
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author Vesoulis, Zachary A.
McPherson, Christopher C.
Whitehead, Halana V.
author_facet Vesoulis, Zachary A.
McPherson, Christopher C.
Whitehead, Halana V.
author_sort Vesoulis, Zachary A.
collection PubMed
description Bronchopulmonary dysplasia (BPD) is a severe pulmonary complication of prematurity and is associated with significant morbidity or death. Early use of systemic corticosteroids may alter the trajectory of the disease and improve outcomes. A BPD Outcomes estimator, developed by the NICHD using a large population dataset, can be used to calculate individual risk. Risk above a certain threshold may indicate that the benefits of corticosteroids outweigh the risks. Empiric analysis of this calculator by systematic entry of synthetic patient information reveals a marked racial disparity; black infants have lower risk of moderate/severe BPD due to a higher risk of death despite equivalent severity of illness. Interpretation and analysis of this finding can be found in “The challenge of risk stratification of preterm infants in the setting of competing and disparate healthcare outcomes” [1]. In this report, we provide the underlying data used in this analysis. Calculator output for 108 example patients, systematically varied by sex, birthweight, race, type of ventilator, and fraction of inspired oxygen (FiO(2)), is reported.
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spelling pubmed-72484472020-05-29 Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset Vesoulis, Zachary A. McPherson, Christopher C. Whitehead, Halana V. Data Brief Medicine and Dentistry Bronchopulmonary dysplasia (BPD) is a severe pulmonary complication of prematurity and is associated with significant morbidity or death. Early use of systemic corticosteroids may alter the trajectory of the disease and improve outcomes. A BPD Outcomes estimator, developed by the NICHD using a large population dataset, can be used to calculate individual risk. Risk above a certain threshold may indicate that the benefits of corticosteroids outweigh the risks. Empiric analysis of this calculator by systematic entry of synthetic patient information reveals a marked racial disparity; black infants have lower risk of moderate/severe BPD due to a higher risk of death despite equivalent severity of illness. Interpretation and analysis of this finding can be found in “The challenge of risk stratification of preterm infants in the setting of competing and disparate healthcare outcomes” [1]. In this report, we provide the underlying data used in this analysis. Calculator output for 108 example patients, systematically varied by sex, birthweight, race, type of ventilator, and fraction of inspired oxygen (FiO(2)), is reported. Elsevier 2020-05-11 /pmc/articles/PMC7248447/ /pubmed/32478148 http://dx.doi.org/10.1016/j.dib.2020.105674 Text en © 2020 The Authors. Published by Elsevier Inc. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Medicine and Dentistry
Vesoulis, Zachary A.
McPherson, Christopher C.
Whitehead, Halana V.
Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset
title Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset
title_full Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset
title_fullStr Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset
title_full_unstemmed Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset
title_short Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset
title_sort racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset
topic Medicine and Dentistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248447/
https://www.ncbi.nlm.nih.gov/pubmed/32478148
http://dx.doi.org/10.1016/j.dib.2020.105674
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