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Hypoxia/reoxygenation activates the JNK pathway and accelerates synovial senescence

Hypoxia/reoxygenation (H/R) may play an important role via senescence in the mechanism of osteoarthritis (OA) development. The synovial membrane is highly sensitive to H/R due to its oxygen consumption feature. Excessive mechanical loads and oxidative stress caused by H/R induce a senescence-associa...

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Detalles Bibliográficos
Autores principales:	Zhang, Yubiao, Zhou, Siqi, Cai, Weisong, Han, Guangtao, Li, Jianping, Chen, Mao, Li, Haohuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248463/ https://www.ncbi.nlm.nih.gov/pubmed/32377698 http://dx.doi.org/10.3892/mmr.2020.11102

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