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The sympathetic transmitter norepinephrine inhibits VSMC proliferation induced by TGFβ by suppressing the expression of the TGFβ receptor ALK5 in aorta remodeling

The sympathetic system is involved in the arterial diseases, but its mechanism remains poorly understood. The present study aimed to explore the impact of the sympathetic neurotransmitter norepinephrine (NE) on transforming growth factor (TGF) β signaling and the role of NE in aortic remodeling. Gua...

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Detalles Bibliográficos
Autores principales: Hu, Zhipeng, Li, Bowen, Wang, Zhiwei, Hu, Xiaoping, Zhang, Min, Chen, Ruoshi, Wu, Qi, Jia, Fangyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248509/
https://www.ncbi.nlm.nih.gov/pubmed/32319652
http://dx.doi.org/10.3892/mmr.2020.11088