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The sympathetic transmitter norepinephrine inhibits VSMC proliferation induced by TGFβ by suppressing the expression of the TGFβ receptor ALK5 in aorta remodeling
The sympathetic system is involved in the arterial diseases, but its mechanism remains poorly understood. The present study aimed to explore the impact of the sympathetic neurotransmitter norepinephrine (NE) on transforming growth factor (TGF) β signaling and the role of NE in aortic remodeling. Gua...
Autores principales: | Hu, Zhipeng, Li, Bowen, Wang, Zhiwei, Hu, Xiaoping, Zhang, Min, Chen, Ruoshi, Wu, Qi, Jia, Fangyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248509/ https://www.ncbi.nlm.nih.gov/pubmed/32319652 http://dx.doi.org/10.3892/mmr.2020.11088 |
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