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Excessive production of mitochondrion-derived reactive oxygen species induced by titanium ions leads to autophagic cell death of osteoblasts via the SIRT3/SOD2 pathway

The incidence of peri-implant bone loss is high, and is a difficult condition to treat. Previous studies have shown that titanium (Ti) ions released from implants can lead to osteoblast cell damage, but the specific mechanisms have not been elucidated. The present study established a Ti ion damage o...

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Detalles Bibliográficos
Autores principales: Wang, Siqian, Yang, Jingyuan, Lin, Tingting, Huang, Shengbing, Ma, Jianfeng, Xu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248520/
https://www.ncbi.nlm.nih.gov/pubmed/32468046
http://dx.doi.org/10.3892/mmr.2020.11094