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Excessive production of mitochondrion-derived reactive oxygen species induced by titanium ions leads to autophagic cell death of osteoblasts via the SIRT3/SOD2 pathway
The incidence of peri-implant bone loss is high, and is a difficult condition to treat. Previous studies have shown that titanium (Ti) ions released from implants can lead to osteoblast cell damage, but the specific mechanisms have not been elucidated. The present study established a Ti ion damage o...
Autores principales: | Wang, Siqian, Yang, Jingyuan, Lin, Tingting, Huang, Shengbing, Ma, Jianfeng, Xu, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248520/ https://www.ncbi.nlm.nih.gov/pubmed/32468046 http://dx.doi.org/10.3892/mmr.2020.11094 |
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