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p53/PGC-1α-mediated mitochondrial dysfunction promotes PC3 prostate cancer cell apoptosis

Data for p53 mutation in prostate cancer in The Cancer Genome Atlas database revealed that >85% of p53 mutations occurred in the p53 DNA binding domain. These mutations not only severely damage the function of the p53 protein, but also reduce the disease-free survival of patients. Peroxisome prol...

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Detalles Bibliográficos
Autores principales:	Li, Jiuling, Li, Yany, Chen, Lanlan, Yu, Bingbing, Xue, Yanan, Guo, Rui, Su, Jing, Liu, Yanan, Sun, Liankun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248533/ https://www.ncbi.nlm.nih.gov/pubmed/32377739 http://dx.doi.org/10.3892/mmr.2020.11121

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