Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils

Mild modification of intravenous immunoglobulin (IVIG) has been reported to result in enhanced polyspecificity and leveraged therapeutic effects in animal models of inflammation. Here, we observed that IVIG modification by ferrous ions, heme or low pH exposure, shifted the repertoires of specificiti...

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Detalles Bibliográficos
Autores principales: Graeter, Stefanie, Schneider, Christoph, Verschoor, Daniëlle, von Däniken, Sandro, Seibold, Frank, Yawalkar, Nikhil, Villiger, Peter, Dimitrov, Jordan D., Smith, David F., Cummings, Richard D., Simon, Hans-Uwe, Vassilev, Tchavdar, von Gunten, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248553/
https://www.ncbi.nlm.nih.gov/pubmed/32508840
http://dx.doi.org/10.3389/fimmu.2020.00973

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