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Innovative Bio-Based Organic UV-A and Blue Light Filters from Meldrum’s Acid
Faced with the ban of some organic UV filters such as octinoxate or avobenzone, especially in Hawaii, it became essential to offer new alternatives that are both renewable and safe for humans and the environment. In this context, a class of bio-based molecules displaying interesting UV filter proper...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248827/ https://www.ncbi.nlm.nih.gov/pubmed/32384797 http://dx.doi.org/10.3390/molecules25092178 |
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author | Peyrot, Cédric Mention, Matthieu M. Brunissen, Fanny Balaguer, Patrick Allais, Florent |
author_facet | Peyrot, Cédric Mention, Matthieu M. Brunissen, Fanny Balaguer, Patrick Allais, Florent |
author_sort | Peyrot, Cédric |
collection | PubMed |
description | Faced with the ban of some organic UV filters such as octinoxate or avobenzone, especially in Hawaii, it became essential to offer new alternatives that are both renewable and safe for humans and the environment. In this context, a class of bio-based molecules displaying interesting UV filter properties and great (photo)stability has been developed from Meldrum’s acid and bio-based and synthetic p-hydroxycinnamic acids, furans and pyrroles. Moreover, p-hydroxycinnamic acid-based Meldrum’s derivatives possess valuable secondary activities sought by the cosmetic industry such as antioxidant and anti-tyrosinase properties. The evaluation of the properties of mixture of judiciously chosen Meldrum’s acid derivatives highlighted the possibility to modulate secondary activity while maintaining excellent UV protection. Meldrum’s acid derivatives are not only competitive when benchmarked against organic filters currently on the market (i.e., avobenzone), but they also do not exhibit any endocrine disruption activity. |
format | Online Article Text |
id | pubmed-7248827 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72488272020-06-10 Innovative Bio-Based Organic UV-A and Blue Light Filters from Meldrum’s Acid Peyrot, Cédric Mention, Matthieu M. Brunissen, Fanny Balaguer, Patrick Allais, Florent Molecules Article Faced with the ban of some organic UV filters such as octinoxate or avobenzone, especially in Hawaii, it became essential to offer new alternatives that are both renewable and safe for humans and the environment. In this context, a class of bio-based molecules displaying interesting UV filter properties and great (photo)stability has been developed from Meldrum’s acid and bio-based and synthetic p-hydroxycinnamic acids, furans and pyrroles. Moreover, p-hydroxycinnamic acid-based Meldrum’s derivatives possess valuable secondary activities sought by the cosmetic industry such as antioxidant and anti-tyrosinase properties. The evaluation of the properties of mixture of judiciously chosen Meldrum’s acid derivatives highlighted the possibility to modulate secondary activity while maintaining excellent UV protection. Meldrum’s acid derivatives are not only competitive when benchmarked against organic filters currently on the market (i.e., avobenzone), but they also do not exhibit any endocrine disruption activity. MDPI 2020-05-06 /pmc/articles/PMC7248827/ /pubmed/32384797 http://dx.doi.org/10.3390/molecules25092178 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Peyrot, Cédric Mention, Matthieu M. Brunissen, Fanny Balaguer, Patrick Allais, Florent Innovative Bio-Based Organic UV-A and Blue Light Filters from Meldrum’s Acid |
title | Innovative Bio-Based Organic UV-A and Blue Light Filters from Meldrum’s Acid |
title_full | Innovative Bio-Based Organic UV-A and Blue Light Filters from Meldrum’s Acid |
title_fullStr | Innovative Bio-Based Organic UV-A and Blue Light Filters from Meldrum’s Acid |
title_full_unstemmed | Innovative Bio-Based Organic UV-A and Blue Light Filters from Meldrum’s Acid |
title_short | Innovative Bio-Based Organic UV-A and Blue Light Filters from Meldrum’s Acid |
title_sort | innovative bio-based organic uv-a and blue light filters from meldrum’s acid |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248827/ https://www.ncbi.nlm.nih.gov/pubmed/32384797 http://dx.doi.org/10.3390/molecules25092178 |
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