Development of UHPLC-MS/MS Method for Indirubin-3′-Oxime Derivative as a Novel FLT3 Inhibitor and Pharmacokinetic Study in Rats

This study aimed to develop and validate a sensitive liquid chromatography-coupled tandem mass spectrometry method for the quantification of LDD-2614, an indirubin derivative and novel FLT3 inhibitor, in rat plasma. In addition, the developed analytical method was applied to observe the pharmacokine...

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Detalles Bibliográficos
Autores principales: Kim, Na Yoon, Kim, Yong-Chul, Kim, Yoon Gyoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248905/
https://www.ncbi.nlm.nih.gov/pubmed/32349415
http://dx.doi.org/10.3390/molecules25092039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248905/
https://www.ncbi.nlm.nih.gov/pubmed/32349415
http://dx.doi.org/10.3390/molecules25092039

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