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Repurposing Zileuton as a Depression Drug Using an AI and In Vitro Approach

Repurposing drugs to target M1 macrophages inflammatory response in depression constitutes a bright alternative for commonly used antidepressants. Depression is a significant type of mood disorder, where patients suffer from pathological disturbances associated with a proinflammatory M1 macrophage p...

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Detalles Bibliográficos
Autores principales: Kubick, Norwin, Pajares, Marta, Enache, Ioana, Manda, Gina, Mickael, Michel-Edwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249014/
https://www.ncbi.nlm.nih.gov/pubmed/32380663
http://dx.doi.org/10.3390/molecules25092155