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A Wearable System to Objectify Assessment of Motor Tasks for Supporting Parkinson’s Disease Diagnosis

Objective assessment of the motor evaluation test for Parkinson’s disease (PD) diagnosis is an open issue both for clinical and technical experts since it could improve current clinical practice with benefits both for patients and healthcare systems. In this work, a wearable system composed of four...

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Detalles Bibliográficos
Autores principales: Rovini, Erika, Maremmani, Carlo, Cavallo, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249017/
https://www.ncbi.nlm.nih.gov/pubmed/32380675
http://dx.doi.org/10.3390/s20092630
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author Rovini, Erika
Maremmani, Carlo
Cavallo, Filippo
author_facet Rovini, Erika
Maremmani, Carlo
Cavallo, Filippo
author_sort Rovini, Erika
collection PubMed
description Objective assessment of the motor evaluation test for Parkinson’s disease (PD) diagnosis is an open issue both for clinical and technical experts since it could improve current clinical practice with benefits both for patients and healthcare systems. In this work, a wearable system composed of four inertial devices (two SensHand and two SensFoot), and related processing algorithms for extracting parameters from limbs motion was tested on 40 healthy subjects and 40 PD patients. Seventy-eight and 96 kinematic parameters were measured from lower and upper limbs, respectively. Statistical and correlation analysis allowed to define four datasets that were used to train and test five supervised learning classifiers. Excellent discrimination between the two groups was obtained with all the classifiers (average accuracy ranging from 0.936 to 0.960) and all the datasets (average accuracy ranging from 0.953 to 0.966), over three conditions that included parameters derived from lower, upper or all limbs. The best performances (accuracy = 1.00) were obtained when classifying all the limbs with linear support vector machine (SVM) or gaussian SVM. Even if further studies should be done, the current results are strongly promising to improve this system as a support tool for clinicians in objectifying PD diagnosis and monitoring.
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spelling pubmed-72490172020-06-10 A Wearable System to Objectify Assessment of Motor Tasks for Supporting Parkinson’s Disease Diagnosis Rovini, Erika Maremmani, Carlo Cavallo, Filippo Sensors (Basel) Article Objective assessment of the motor evaluation test for Parkinson’s disease (PD) diagnosis is an open issue both for clinical and technical experts since it could improve current clinical practice with benefits both for patients and healthcare systems. In this work, a wearable system composed of four inertial devices (two SensHand and two SensFoot), and related processing algorithms for extracting parameters from limbs motion was tested on 40 healthy subjects and 40 PD patients. Seventy-eight and 96 kinematic parameters were measured from lower and upper limbs, respectively. Statistical and correlation analysis allowed to define four datasets that were used to train and test five supervised learning classifiers. Excellent discrimination between the two groups was obtained with all the classifiers (average accuracy ranging from 0.936 to 0.960) and all the datasets (average accuracy ranging from 0.953 to 0.966), over three conditions that included parameters derived from lower, upper or all limbs. The best performances (accuracy = 1.00) were obtained when classifying all the limbs with linear support vector machine (SVM) or gaussian SVM. Even if further studies should be done, the current results are strongly promising to improve this system as a support tool for clinicians in objectifying PD diagnosis and monitoring. MDPI 2020-05-05 /pmc/articles/PMC7249017/ /pubmed/32380675 http://dx.doi.org/10.3390/s20092630 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Rovini, Erika
Maremmani, Carlo
Cavallo, Filippo
A Wearable System to Objectify Assessment of Motor Tasks for Supporting Parkinson’s Disease Diagnosis
title A Wearable System to Objectify Assessment of Motor Tasks for Supporting Parkinson’s Disease Diagnosis
title_full A Wearable System to Objectify Assessment of Motor Tasks for Supporting Parkinson’s Disease Diagnosis
title_fullStr A Wearable System to Objectify Assessment of Motor Tasks for Supporting Parkinson’s Disease Diagnosis
title_full_unstemmed A Wearable System to Objectify Assessment of Motor Tasks for Supporting Parkinson’s Disease Diagnosis
title_short A Wearable System to Objectify Assessment of Motor Tasks for Supporting Parkinson’s Disease Diagnosis
title_sort wearable system to objectify assessment of motor tasks for supporting parkinson’s disease diagnosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249017/
https://www.ncbi.nlm.nih.gov/pubmed/32380675
http://dx.doi.org/10.3390/s20092630
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