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Dysregulation of type I interferon responses in COVID-19
Infection with SARS-CoV-2 can lead to excessive production of pro-inflammatory cytokines, but the production of type I interferons, which are key antiviral mediators, is reportedly blunted. Here, we discuss how imbalanced interferon responses may contribute to the pathology of COVID-19.
Autores principales: | Acharya, Dhiraj, Liu, GuanQun, Gack, Michaela U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249038/ https://www.ncbi.nlm.nih.gov/pubmed/32457522 http://dx.doi.org/10.1038/s41577-020-0346-x |
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