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Solubility Data and Computational Modeling of Baricitinib in Various (DMSO + Water) Mixtures

The solubility and thermodynamic analysis of baricitinib (BNB) in various dimethyl sulfoxide (DMSO) + water mixtures were performed. The “mole fraction solubilities (x(e))” of BNB in DMSO and water mixtures were determined at “T = 298.2–323.2 K” and “p = 0.1 MPa” using an isothermal saturation techn...

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Detalles Bibliográficos
Autores principales: M. Alshahrani, Saad, Shakeel, Faiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249174/
https://www.ncbi.nlm.nih.gov/pubmed/32370021
http://dx.doi.org/10.3390/molecules25092124