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Accounting for cell type hierarchy in evaluating single cell RNA-seq clustering
Cell clustering is one of the most common routines in single cell RNA-seq data analyses, for which a number of specialized methods are available. The evaluation of these methods ignores an important biological characteristic that the structure for a population of cells is hierarchical, which could r...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249323/ https://www.ncbi.nlm.nih.gov/pubmed/32450895 http://dx.doi.org/10.1186/s13059-020-02027-x |