Therapeutic strategies against hDOT1L as a potential drug target in MLL-rearranged leukemias

Therapeutic intervention of proteins participating in chromatin-mediated signaling with small-molecules is a novel option to reprogram expression networks for restraining disease states. Protein methyltransferases form the prominent family of such proteins regulating gene expression via epigenetic m...

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Detalles Bibliográficos
Autores principales: Banday, Shahid, Farooq, Zeenat, Ganai, Shabir Ahmad, Altaf, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249331/
https://www.ncbi.nlm.nih.gov/pubmed/32450905
http://dx.doi.org/10.1186/s13148-020-00860-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249331/
https://www.ncbi.nlm.nih.gov/pubmed/32450905
http://dx.doi.org/10.1186/s13148-020-00860-2

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