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Therapeutic strategies against hDOT1L as a potential drug target in MLL-rearranged leukemias
Therapeutic intervention of proteins participating in chromatin-mediated signaling with small-molecules is a novel option to reprogram expression networks for restraining disease states. Protein methyltransferases form the prominent family of such proteins regulating gene expression via epigenetic m...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249331/ https://www.ncbi.nlm.nih.gov/pubmed/32450905 http://dx.doi.org/10.1186/s13148-020-00860-2 |