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SCSIM: Jointly simulating correlated single-cell and bulk next-generation DNA sequencing data
BACKGROUND: Recently, it has become possible to collect next-generation DNA sequencing data sets that are composed of multiple samples from multiple biological units where each of these samples may be from a single cell or bulk tissue. Yet, there does not yet exist a tool for simulating DNA sequenci...
Autores principales: | Giguere, Collin, Dubey, Harsh Vardhan, Sarsani, Vishal Kumar, Saddiki, Hachem, He, Shai, Flaherty, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249349/ https://www.ncbi.nlm.nih.gov/pubmed/32456609 http://dx.doi.org/10.1186/s12859-020-03550-1 |
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