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Analysis of responder-based endpoints: improving power through utilising continuous components

BACKGROUND: Clinical trials and other studies commonly assess the effectiveness of an intervention through the use of responder-based endpoints. These classify patients based on whether they meet a number of criteria which often involve continuous variables categorised as being above or below a thre...

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Detalles Bibliográficos
Autores principales: Wason, James, McMenamin, Martina, Dodd, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249409/
https://www.ncbi.nlm.nih.gov/pubmed/32450909
http://dx.doi.org/10.1186/s13063-020-04353-8