Cargando…
Analysis of responder-based endpoints: improving power through utilising continuous components
BACKGROUND: Clinical trials and other studies commonly assess the effectiveness of an intervention through the use of responder-based endpoints. These classify patients based on whether they meet a number of criteria which often involve continuous variables categorised as being above or below a thre...
Autores principales: | Wason, James, McMenamin, Martina, Dodd, Susanna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249409/ https://www.ncbi.nlm.nih.gov/pubmed/32450909 http://dx.doi.org/10.1186/s13063-020-04353-8 |
Ejemplares similares
-
Increasing power in the analysis of responder endpoints in rheumatology: a software tutorial
por: McMenamin, Martina, et al.
Publicado: (2021) -
Improving the analysis of composite endpoints in rare disease trials
por: McMenamin, Martina, et al.
Publicado: (2018) -
Employing a latent variable framework to improve efficiency in composite endpoint analysis
por: McMenamin, Martina, et al.
Publicado: (2020) -
Sample size estimation using a latent variable model for mixed outcome co‐primary, multiple primary and composite endpoints
por: McMenamin, Martina E., et al.
Publicado: (2022) -
Improving power in PSA response analyses of metastatic castration-resistant prostate cancer trials
por: Grayling, Michael J., et al.
Publicado: (2022)