Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/NLRP3 signaling in rat

BACKGROUND: Recently, depression has been identified as a prevalent and severe mental disorder. However, the mechanisms underlying the depression risk remain elusive. The neuroinflammation and NLRP3 inflammasome activation are known to be involved in the pathology of depression. Dihydrolipoic acid (...

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Detalles Bibliográficos
Autores principales: Bian, Hetao, Wang, Gaohua, Huang, Junjie, Liang, Liang, Zheng, Yage, Wei, Yanyan, Wang, Hui, Xiao, Ling, Wang, Huiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249417/
https://www.ncbi.nlm.nih.gov/pubmed/32450903
http://dx.doi.org/10.1186/s12974-020-01836-y

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