Cargando…

Microenvironment characterization and multi-omics signatures related to prognosis and immunotherapy response of hepatocellular carcinoma

BACKGROUND: Immune cell infiltration in the tumor microenvironment (TME) affects tumor initiation, patients’ prognosis and immunotherapy strategies. However, their roles and interactions with genomics and molecular processes in hepatocellular carcinoma (HCC) still have not been systematically evalua...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Furong, Qin, Lu, Liao, Zhibin, Song, Jia, Yuan, Chaoyi, Liu, Yachong, Wang, Yu, Xu, Heze, Zhang, Qiaofeng, Pei, Youliang, Zhang, Hongwei, Pan, Yonglong, Chen, Xiaoping, Zhang, Zhanguo, Zhang, Wanguang, Zhang, Bixiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249423/ https://www.ncbi.nlm.nih.gov/pubmed/32509418 http://dx.doi.org/10.1186/s40164-020-00165-3

Ejemplares similares

The importance of N6-methyladenosine modification in tumor immunity and immunotherapy
por: Zhang, Ze, et al.
Publicado: (2022)

ACE2 Expression in Pancreas May Cause Pancreatic Damage After SARS-CoV-2 Infection
por: Liu, Furong, et al.
Publicado: (2020)

Long noncoding RNA HOXC-AS3 interacts with CDK2 to promote proliferation in hepatocellular carcinoma
por: Su, Chen, et al.
Publicado: (2022)

Clinically significant portal hypertension in cirrhosis patients with COVID-19: Clinical characteristics and outcomes
por: Liu, Furong, et al.
Publicado: (2020)

ALKBH5 prevents hepatocellular carcinoma progression by post-transcriptional inhibition of PAQR4 in an m6A dependent manner
por: Wang, Weijian, et al.
Publicado: (2023)

Targeting VPS72 inhibits ACTL6A/MYC axis activity in HCC progression
por: Liu, Furong, et al.
Publicado: (2023)

Long non-coding RNA CCDC183-AS1 acts AS a miR-589-5p sponge to promote the progression of hepatocellular carcinoma through regulating SKP1 expression
por: Zhu, He, et al.
Publicado: (2021)

Structures and biological functions of zinc finger proteins and their roles in hepatocellular carcinoma
por: Li, Xinxin, et al.
Publicado: (2022)

ALKBH5-mediated m(6)A modification of lincRNA LINC02551 enhances the stability of DDX24 to promote hepatocellular carcinoma growth and metastasis
por: Zhang, Hongwei, et al.
Publicado: (2022)

EIF4A3-induced circTOLLIP promotes the progression of hepatocellular carcinoma via the miR-516a-5p/PBX3/EMT pathway
por: Liu, Yachong, et al.
Publicado: (2022)

Benefits of Splenectomy and Curative Treatments for Patients with Hepatocellular Carcinoma and Portal Hypertension: a Retrospective Study
por: Pei, Youliang, et al.
Publicado: (2018)

A micropeptide JunBP regulated by TGF-β promotes hepatocellular carcinoma metastasis
por: Zhang, Hongwei, et al.
Publicado: (2022)

Characterization of TGFβ-associated molecular features and drug responses in gastrointestinal adenocarcinoma
por: Zhang, Qiaofeng, et al.
Publicado: (2021)

Improved survival following splenectomy combined with curative treatments for hepatocellular carcinoma in Child B patients: A propensity score matching study
por: Pei, Youliang, et al.
Publicado: (2019)

The role of RNA m(5)C modification in cancer metastasis
por: Zhang, Qiaofeng, et al.
Publicado: (2021)

Long noncoding RNA SNHG14 promotes hepatocellular carcinoma progression by regulating miR-876-5p/SSR2 axis
por: Liao, Zhibin, et al.
Publicado: (2021)

The role of YAP1 in liver cancer stem cells: proven and potential mechanisms
por: Wu, Haofeng, et al.
Publicado: (2022)

Incomplete radiofrequency ablation provokes colorectal cancer liver metastases through heat shock response by PKCα/Fra-1 pathway
por: Zhang, Zhanguo, et al.
Publicado: (2019)

EZH2 in hepatocellular carcinoma: progression, immunity, and potential targeting therapies
por: Wang, Bohan, et al.
Publicado: (2023)

Modulation of the TGF-β signaling pathway by long noncoding RNA in hepatocellular carcinoma
por: Han, Mengzhen, et al.
Publicado: (2020)

CRISPR/Cas9‐mediated knockout of HBsAg inhibits proliferation and tumorigenicity of HBV‐positive hepatocellular carcinoma cells
por: Song, Jia, et al.
Publicado: (2018)

Circular RNA circUBE2J2 acts as the sponge of microRNA-370-5P to suppress hepatocellular carcinoma progression
por: Zhang, Lu, et al.
Publicado: (2021)

The 14-3-3σ protein promotes HCC anoikis resistance by inhibiting EGFR degradation and thereby activating the EGFR-dependent ERK1/2 signaling pathway
por: Song, Jia, et al.
Publicado: (2021)

Long noncoding RNA HULC promotes hepatocellular carcinoma progression
por: Zhang, Hongwei, et al.
Publicado: (2019)

Construction and Validation of a Nomogram for Predicting the Risk of Deep Vein Thrombosis in Hepatocellular Carcinoma Patients After Laparoscopic Hepatectomy: A Retrospective Study
por: Chen, Yao, et al.
Publicado: (2021)

Infrahepatic inferior vena cava clamping with Pringle maneuvers for laparoscopic extracapsular enucleation of giant liver hemangiomas
por: Zhang, Wanguang, et al.
Publicado: (2017)

miR-631 Inhibits Intrahepatic Metastasis of Hepatocellular Carcinoma by Targeting PTPRE
por: Chen, Bingqing, et al.
Publicado: (2020)

A 4 and a half years old boy with mesenchymal hamartomas in the left lateral lobe of the liver: A case report and literature review
por: Liao, Wei, et al.
Publicado: (2017)

DDR1 promotes hepatocellular carcinoma metastasis through recruiting PSD4 to ARF6
por: Zhang, Xiaochao, et al.
Publicado: (2022)

Title: Multi-Omics and Immune Landscape of Proliferative LncRNA Signatures: Implications for Risk Stratification and Immunotherapy in Hepatocellular Carcinoma
por: Liu, Chi, et al.
Publicado: (2022)

Upregulation of liver kinase B1 predicts poor prognosis in hepatocellular carcinoma
por: Tan, Xiaolong, et al.
Publicado: (2018)

High PLK4 expression promotes tumor progression and induces epithelial-mesenchymal transition by regulating the Wnt/β-catenin signaling pathway in colorectal cancer
por: Liao, Zhibin, et al.
Publicado: (2018)

High PLK4 expression promotes tumor progression and induces epithelial-mesenchymal transition by regulating the Wnt/β-catenin signaling pathway in colorectal cancer
por: Liao, Zhibin, et al.
Publicado: (2021)

High PLK4 expression promotes tumor progression and induces epithelial-mesenchymal transition by regulating the Wnt/β-catenin signaling pathway in colorectal cancer
por: Liao, Zhibin, et al.
Publicado: (2021)

Multi-omic analysis of glycolytic signatures: exploring the predictive significance of heterogeneity and stemness in immunotherapy response and outcomes in hepatocellular carcinoma
por: Zhang, Shiyu, et al.
Publicado: (2023)

Integrated multi-omics identified the novel intratumor microbiome-derived subtypes and signature to predict the outcome, tumor microenvironment heterogeneity, and immunotherapy response for pancreatic cancer patients
por: Zhang, Biao, et al.
Publicado: (2023)

TRIM proteins in hepatocellular carcinoma
por: Lu, Kan, et al.
Publicado: (2022)

14–3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling
por: Song, Jia, et al.
Publicado: (2019)

N6-Methyladenine-Related Signature for Immune Microenvironment and Response to Immunotherapy in Hepatocellular Carcinoma
por: Ren, Shao-hua, et al.
Publicado: (2022)

Signatures of Multi-Omics Reveal Distinct Tumor Immune Microenvironment Contributing to Immunotherapy in Lung Adenocarcinoma
por: Huang, Ziqi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_snn69d4jf9n9ve3ioepu18f82h