Cargando…

Inhibition of transforming growth factor beta signaling pathway promotes differentiation of human induced pluripotent stem cell-derived brain microvascular endothelial-like cells

BACKGROUND: The blood–brain barrier (BBB) plays an important role as a biological barrier by regulating molecular transport between circulating blood and the brain parenchyma. In drug development, the accurate evaluation of BBB permeability is essential to predict not only the efficacy but also the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamashita, Misaki, Aoki, Hiromasa, Hashita, Tadahiro, Iwao, Takahiro, Matsunaga, Tamihide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249446/ https://www.ncbi.nlm.nih.gov/pubmed/32456699 http://dx.doi.org/10.1186/s12987-020-00197-1

Ejemplares similares

Laminin 221 fragment is suitable for the differentiation of human induced pluripotent stem cells into brain microvascular endothelial-like cells with robust barrier integrity
por: Aoki, Hiromasa, et al.
Publicado: (2020)

Generation of Brain Microvascular Endothelial-like Cells from Human iPS Cell-Derived Endothelial Progenitor Cells Using TGF-β Receptor Inhibitor, Laminin 511 Fragment, and Neuronal Cell Culture Supplements
por: Aoki, Hiromasa, et al.
Publicado: (2022)

Efficient differentiation and purification of human induced pluripotent stem cell-derived endothelial progenitor cells and expansion with the use of inhibitors of ROCK, TGF-β, and GSK3β
por: Aoki, Hiromasa, et al.
Publicado: (2020)

Establishment of a novel culture method for maintaining intestinal stem cells derived from human induced pluripotent stem cells
por: Kondo, Satoshi, et al.
Publicado: (2020)

Effects of human induced pluripotent stem cell-derived intestinal organoids on colitis-model mice
por: Nakanishi, Anna, et al.
Publicado: (2022)

Gellan Gum Promotes the Differentiation of Enterocytes from Human Induced Pluripotent Stem Cells
por: Qiu, Shimeng, et al.
Publicado: (2020)

An Efficient Method for the Differentiation of Human iPSC-Derived Endoderm toward Enterocytes and Hepatocytes
por: Qiu, Shimeng, et al.
Publicado: (2021)

Protective Effect of Irsogladine against Aspirin-Induced Mucosal Injury in Human Induced Pluripotent Stem Cell-Derived Small Intestine
por: Kanno, Takuya, et al.
Publicado: (2022)

Histone Deacetylase Inhibitor Valproic Acid Promotes the Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-Like Cells
por: Kondo, Yuki, et al.
Publicado: (2014)

Aβ42 treatment of the brain side reduced the level of flotillin from endothelial cells on the blood side via FGF-2 signaling in a blood–brain barrier model
por: Nakamura, Tomohisa, et al.
Publicado: (2023)

Ivermectin Inhibits HBV Entry into the Nucleus by Suppressing KPNA2
por: Nakanishi, Anna, et al.
Publicado: (2022)

Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions
por: Nishihara, Hideaki, et al.
Publicado: (2021)

Induced pluripotent stem cell-derived cells model brain microvascular endothelial cell glucose metabolism
por: Weber, Callie M., et al.
Publicado: (2022)

Generation of Brain Microvascular Endothelial-Like Cells from Human Induced Pluripotent Stem Cells by Co-Culture with C6 Glioma Cells
por: Minami, Haruka, et al.
Publicado: (2015)

Exploring the effects of cell seeding density on the differentiation of human pluripotent stem cells to brain microvascular endothelial cells
por: Wilson, Hannah K, et al.
Publicado: (2015)

Effective endothelial cell and human pluripotent stem cell interactions generate functional insulin-producing beta cells
por: Talavera-Adame, Dodanim, et al.
Publicado: (2016)

Therapeutic Potency of Induced Pluripotent Stem-Cell-Derived Corneal Endothelial-like Cells for Corneal Endothelial Dysfunction
por: So, Seongjun, et al.
Publicado: (2022)

Corneal Endothelial-like Cells Derived from Induced Pluripotent Stem Cells for Cell Therapy
por: Ng, Xiao Yu, et al.
Publicado: (2023)

Derivation of Brain Capillary-like Endothelial Cells from Human Pluripotent Stem Cell-Derived Endothelial Progenitor Cells
por: Praça, Catarina, et al.
Publicado: (2019)

Human microvascular endothelial cells use beta 1 and beta 3 integrin receptor complexes to attach to laminin
Publicado: (1990)

Evaluating the potential of endothelial cells derived from human induced pluripotent stem cells to form microvascular networks in 3D cultures
por: Bezenah, Jonathan R., et al.
Publicado: (2018)

Tolloid‐Like 1 Negatively Regulates Hepatic Differentiation of Human Induced Pluripotent Stem Cells Through Transforming Growth Factor Beta Signaling
por: Kiso, Ayumi, et al.
Publicado: (2020)

Induced pluripotent stem cells are induced pluripotent stem cell-like cells
por: Song, Liting, et al.
Publicado: (2015)

Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells
por: Cheng, LinXi, et al.
Publicado: (2021)

Generation of induced pluripotent stem cell-derived beta-cells in blood amino acids-like medium
por: Ali, Marwa, et al.
Publicado: (2023)

PT712. Functional expression of choline transporter like-protein 1 (CTL1) and CTL2 in human brain microvascular endothelial cells
por: Iwao, Beniko, et al.
Publicado: (2016)

PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells
por: De Smedt, Jonathan, et al.
Publicado: (2021)

Thymosin beta-4 improves endothelial function and reparative potency of diabetic endothelial cells differentiated from patient induced pluripotent stem cells
por: Su, Liping, et al.
Publicado: (2022)

An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons
por: Canfield, Scott G., et al.
Publicado: (2019)

TGF-β and SHH Regulate Pluripotent Stem Cell Differentiation into Brain Microvascular Endothelial Cells in Generating an In Vitro Blood–Brain Barrier Model
por: Lee, Na Geum, et al.
Publicado: (2023)

Human pluripotent stem cell‐derived epicardial progenitors can differentiate to endocardial‐like endothelial cells
por: Bao, Xiaoping, et al.
Publicado: (2017)

Differentiation of beta-like cells from human induced pluripotent stem cell-derived pancreatic progenitor organoids
por: Pedraza-Arevalo, Sergio, et al.
Publicado: (2022)

Correction to: An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons
por: Canfield, Scott G., et al.
Publicado: (2019)

Prediction of Drug Permeability Using In Vitro Blood–Brain Barrier Models with Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells
por: Ohshima, Makiko, et al.
Publicado: (2019)

Microvascular endothelial cells of the corpus luteum
por: Davis, John S, et al.
Publicado: (2003)

Aneuploidy in pluripotent stem cells and implications for cancerous transformation
por: Na, Jie, et al.
Publicado: (2014)

Directed Differentiation of Human Pluripotent Stem Cells towards Corneal Endothelial-Like Cells under Defined Conditions
por: Grönroos, Pyry, et al.
Publicado: (2021)

Role of microvascular endothelial cells on proliferation, migration and adhesion of hematopoietic stem cells
por: Lin, Fanli, et al.
Publicado: (2020)

Radiation-induced apoptosis in microvascular endothelial cells.
por: Langley, R. E., et al.
Publicado: (1997)

Brain microvascular endothelial cells derived from human induced pluripotent stem cells as in vitro model for assessing blood-brain barrier transferrin receptor-mediated transcytosis
por: Piantino, Marie, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j6up98a2bml353em11nlddsjg7