Farnesoid X receptor knockout protects brain against ischemic injury through reducing neuronal apoptosis in mice

BACKGROUND: Farnesoid X receptor (FXR) is a nuclear receptor that plays a critical role in controlling cell apoptosis in diverse diseases. Previous studies have shown that knocking out FXR improved cardiac function by reducing cardiomyocyte apoptosis in myocardial ischemic mice. However, the role of...

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Detalles Bibliográficos
Autores principales: Shan, Hui-Min, Zang, Minhua, Zhang, Qi, Shi, Ru-Bing, Shi, Xiao-Jing, Mamtilahun, Muyassar, Liu, Chang, Luo, Long-long, Tian, Xiaoying, Zhang, Zhijun, Yang, Guo-Yuan, Tang, Yaohui, Pu, Jun, Wang, Yongting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249620/
https://www.ncbi.nlm.nih.gov/pubmed/32450881
http://dx.doi.org/10.1186/s12974-020-01838-w

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