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EZH2-inhibitor DZNep enhances apoptosis of renal tubular epithelial cells in presence and absence of cisplatin

BACKGROUND: The enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase and induces the trimethylation of histone H3 lysine 27 (H3K27me3) in the promoter of many key genes; EZH2 acts as a transcriptional repressor and is an epigenetic regulator for several cancers. However, the role of EZH...

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Detalles Bibliográficos
Autores principales:	Chen, Si-qi, Li, Jia-qi, Wang, Xiao-qiao, Lei, Wen-jing, Li, Hao, Wan, Jiao, Hu, Zheng, Zou, Yao-wei, Wu, Xiao-yu, Niu, Hong-xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249628/ https://www.ncbi.nlm.nih.gov/pubmed/32508971 http://dx.doi.org/10.1186/s13008-020-00064-3

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