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Recurrent meningococcal meningitis with complement 6 (C6) deficiency: A case report

RATIONALE: Late complement deficiency increases susceptibility to meningococcal disease and recurrent infections. In Korea, 5 case reports have described meningococcal disease with complement deficiency. However, C6 deficiency has not been described previously. PATIENT CONCERNS: A 21-year-old police...

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Autores principales: Bae, Ji Yun, Ham, Ahrong, Choi, Hee Jung, Kim, Chung-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249908/
https://www.ncbi.nlm.nih.gov/pubmed/32481330
http://dx.doi.org/10.1097/MD.0000000000020362
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author Bae, Ji Yun
Ham, Ahrong
Choi, Hee Jung
Kim, Chung-Jong
author_facet Bae, Ji Yun
Ham, Ahrong
Choi, Hee Jung
Kim, Chung-Jong
author_sort Bae, Ji Yun
collection PubMed
description RATIONALE: Late complement deficiency increases susceptibility to meningococcal disease and recurrent infections. In Korea, 5 case reports have described meningococcal disease with complement deficiency. However, C6 deficiency has not been described previously. PATIENT CONCERNS: A 21-year-old police trainee presented with recurrent meningococcal meningitis. He was housed in communal living quarters until 20 days before the initial symptom onset. DIAGNOSIS: He was diagnosed with meningococcal meningitis with C6 deficiency. INTERVENTIONS: He was treated with intravenous ceftriaxone. An additional dose of quadrivalent meningococcal conjugate vaccine was administered after discharge. OUTCOMES: He was discharged without complications. LESSONS: Screening for complement deficiency is necessary in patients with a history of recurrent meningococcal infections to provide appropriate care and prevent recurrent infections.
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spelling pubmed-72499082020-06-15 Recurrent meningococcal meningitis with complement 6 (C6) deficiency: A case report Bae, Ji Yun Ham, Ahrong Choi, Hee Jung Kim, Chung-Jong Medicine (Baltimore) 4900 RATIONALE: Late complement deficiency increases susceptibility to meningococcal disease and recurrent infections. In Korea, 5 case reports have described meningococcal disease with complement deficiency. However, C6 deficiency has not been described previously. PATIENT CONCERNS: A 21-year-old police trainee presented with recurrent meningococcal meningitis. He was housed in communal living quarters until 20 days before the initial symptom onset. DIAGNOSIS: He was diagnosed with meningococcal meningitis with C6 deficiency. INTERVENTIONS: He was treated with intravenous ceftriaxone. An additional dose of quadrivalent meningococcal conjugate vaccine was administered after discharge. OUTCOMES: He was discharged without complications. LESSONS: Screening for complement deficiency is necessary in patients with a history of recurrent meningococcal infections to provide appropriate care and prevent recurrent infections. Wolters Kluwer Health 2020-05-22 /pmc/articles/PMC7249908/ /pubmed/32481330 http://dx.doi.org/10.1097/MD.0000000000020362 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 4900
Bae, Ji Yun
Ham, Ahrong
Choi, Hee Jung
Kim, Chung-Jong
Recurrent meningococcal meningitis with complement 6 (C6) deficiency: A case report
title Recurrent meningococcal meningitis with complement 6 (C6) deficiency: A case report
title_full Recurrent meningococcal meningitis with complement 6 (C6) deficiency: A case report
title_fullStr Recurrent meningococcal meningitis with complement 6 (C6) deficiency: A case report
title_full_unstemmed Recurrent meningococcal meningitis with complement 6 (C6) deficiency: A case report
title_short Recurrent meningococcal meningitis with complement 6 (C6) deficiency: A case report
title_sort recurrent meningococcal meningitis with complement 6 (c6) deficiency: a case report
topic 4900
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249908/
https://www.ncbi.nlm.nih.gov/pubmed/32481330
http://dx.doi.org/10.1097/MD.0000000000020362
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