Cargando…
Successful dabigatran reversal after subdural hemorrhage using idarucizumab in a mobile stroke unit: A case report
RATIONALE: Idarucizumab is a specific reversal agent for patients with bleeding related to the anticoagulant dabigatran. There are no prior descriptions of Idarucizumab administration in the prehospital setting for intracranial hemorrhage. PATIENT CONCERNS: An 82-year-old woman treated with dabigatr...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249931/ https://www.ncbi.nlm.nih.gov/pubmed/32481289 http://dx.doi.org/10.1097/MD.0000000000020200 |
_version_ | 1783538677906931712 |
---|---|
author | Thirunavukkarasu, Sibi Kalashyan, Hayrapet Jickling, Glen Jeerakathil, Thomas Joseph Jayaprakash, Harsha Kamble Buck, Brian H. Shuaib, Ashfaq Butcher, Ken |
author_facet | Thirunavukkarasu, Sibi Kalashyan, Hayrapet Jickling, Glen Jeerakathil, Thomas Joseph Jayaprakash, Harsha Kamble Buck, Brian H. Shuaib, Ashfaq Butcher, Ken |
author_sort | Thirunavukkarasu, Sibi |
collection | PubMed |
description | RATIONALE: Idarucizumab is a specific reversal agent for patients with bleeding related to the anticoagulant dabigatran. There are no prior descriptions of Idarucizumab administration in the prehospital setting for intracranial hemorrhage. PATIENT CONCERNS: An 82-year-old woman treated with dabigatran for atrial fibrillation developed acute focal weakness. This led to activation of emergency medical services and assessment in the mobile stroke unit (MSU). DIAGNOSIS: Computed tomography of the brain performed in the MSU revealed an acute subdural hematoma. INTERVENTIONS: The patient was treated with Idarucizumab in the MSU. OUTCOMES: The subdural hematoma was treated with a burr hole evacuation and the patient was discharged to a rehabilitation facility without residual focal neurological deficits. LESSONS: Idarucizumab can be used safely and effectively to treat dabigatran-associated intracranial hemorrhage in the prehospital setting. |
format | Online Article Text |
id | pubmed-7249931 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-72499312020-06-15 Successful dabigatran reversal after subdural hemorrhage using idarucizumab in a mobile stroke unit: A case report Thirunavukkarasu, Sibi Kalashyan, Hayrapet Jickling, Glen Jeerakathil, Thomas Joseph Jayaprakash, Harsha Kamble Buck, Brian H. Shuaib, Ashfaq Butcher, Ken Medicine (Baltimore) 5300 RATIONALE: Idarucizumab is a specific reversal agent for patients with bleeding related to the anticoagulant dabigatran. There are no prior descriptions of Idarucizumab administration in the prehospital setting for intracranial hemorrhage. PATIENT CONCERNS: An 82-year-old woman treated with dabigatran for atrial fibrillation developed acute focal weakness. This led to activation of emergency medical services and assessment in the mobile stroke unit (MSU). DIAGNOSIS: Computed tomography of the brain performed in the MSU revealed an acute subdural hematoma. INTERVENTIONS: The patient was treated with Idarucizumab in the MSU. OUTCOMES: The subdural hematoma was treated with a burr hole evacuation and the patient was discharged to a rehabilitation facility without residual focal neurological deficits. LESSONS: Idarucizumab can be used safely and effectively to treat dabigatran-associated intracranial hemorrhage in the prehospital setting. Wolters Kluwer Health 2020-05-22 /pmc/articles/PMC7249931/ /pubmed/32481289 http://dx.doi.org/10.1097/MD.0000000000020200 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 5300 Thirunavukkarasu, Sibi Kalashyan, Hayrapet Jickling, Glen Jeerakathil, Thomas Joseph Jayaprakash, Harsha Kamble Buck, Brian H. Shuaib, Ashfaq Butcher, Ken Successful dabigatran reversal after subdural hemorrhage using idarucizumab in a mobile stroke unit: A case report |
title | Successful dabigatran reversal after subdural hemorrhage using idarucizumab in a mobile stroke unit: A case report |
title_full | Successful dabigatran reversal after subdural hemorrhage using idarucizumab in a mobile stroke unit: A case report |
title_fullStr | Successful dabigatran reversal after subdural hemorrhage using idarucizumab in a mobile stroke unit: A case report |
title_full_unstemmed | Successful dabigatran reversal after subdural hemorrhage using idarucizumab in a mobile stroke unit: A case report |
title_short | Successful dabigatran reversal after subdural hemorrhage using idarucizumab in a mobile stroke unit: A case report |
title_sort | successful dabigatran reversal after subdural hemorrhage using idarucizumab in a mobile stroke unit: a case report |
topic | 5300 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249931/ https://www.ncbi.nlm.nih.gov/pubmed/32481289 http://dx.doi.org/10.1097/MD.0000000000020200 |
work_keys_str_mv | AT thirunavukkarasusibi successfuldabigatranreversalaftersubduralhemorrhageusingidarucizumabinamobilestrokeunitacasereport AT kalashyanhayrapet successfuldabigatranreversalaftersubduralhemorrhageusingidarucizumabinamobilestrokeunitacasereport AT jicklingglen successfuldabigatranreversalaftersubduralhemorrhageusingidarucizumabinamobilestrokeunitacasereport AT jeerakathilthomasjoseph successfuldabigatranreversalaftersubduralhemorrhageusingidarucizumabinamobilestrokeunitacasereport AT jayaprakashharshakamble successfuldabigatranreversalaftersubduralhemorrhageusingidarucizumabinamobilestrokeunitacasereport AT buckbrianh successfuldabigatranreversalaftersubduralhemorrhageusingidarucizumabinamobilestrokeunitacasereport AT shuaibashfaq successfuldabigatranreversalaftersubduralhemorrhageusingidarucizumabinamobilestrokeunitacasereport AT butcherken successfuldabigatranreversalaftersubduralhemorrhageusingidarucizumabinamobilestrokeunitacasereport |