A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response

We report the case of a patient who had travelled to Japan and who presented mild respiratory symptoms during the COVID-19 outbreak period. There was transient existence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in his oropharynx. The RNA was absent in the six respiratory s...

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Autores principales: Lin, Yi-Chun, Cheng, Chien-Yu, Chen, Cheng-Pin, Cheng, Shu-Hsing, Chang, Sui-Yuan, Hsueh, Po-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250069/
https://www.ncbi.nlm.nih.gov/pubmed/32470604
http://dx.doi.org/10.1016/j.ijid.2020.05.070
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author Lin, Yi-Chun
Cheng, Chien-Yu
Chen, Cheng-Pin
Cheng, Shu-Hsing
Chang, Sui-Yuan
Hsueh, Po-Ren
author_facet Lin, Yi-Chun
Cheng, Chien-Yu
Chen, Cheng-Pin
Cheng, Shu-Hsing
Chang, Sui-Yuan
Hsueh, Po-Ren
author_sort Lin, Yi-Chun
collection PubMed
description We report the case of a patient who had travelled to Japan and who presented mild respiratory symptoms during the COVID-19 outbreak period. There was transient existence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in his oropharynx. The RNA was absent in the six respiratory specimens that were subsequently tested. An anti-SARS-CoV-2 antibody response was absent in the acute and convalescent sera. The reported case indicates that transient colonization of SARS-CoV-2 in the upper respiratory tract is possible without inciting any antibody response against the virus.
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spelling pubmed-72500692020-05-27 A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response Lin, Yi-Chun Cheng, Chien-Yu Chen, Cheng-Pin Cheng, Shu-Hsing Chang, Sui-Yuan Hsueh, Po-Ren Int J Infect Dis Case Report We report the case of a patient who had travelled to Japan and who presented mild respiratory symptoms during the COVID-19 outbreak period. There was transient existence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in his oropharynx. The RNA was absent in the six respiratory specimens that were subsequently tested. An anti-SARS-CoV-2 antibody response was absent in the acute and convalescent sera. The reported case indicates that transient colonization of SARS-CoV-2 in the upper respiratory tract is possible without inciting any antibody response against the virus. The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020-07 2020-05-26 /pmc/articles/PMC7250069/ /pubmed/32470604 http://dx.doi.org/10.1016/j.ijid.2020.05.070 Text en © 2020 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Lin, Yi-Chun
Cheng, Chien-Yu
Chen, Cheng-Pin
Cheng, Shu-Hsing
Chang, Sui-Yuan
Hsueh, Po-Ren
A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response
title A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response
title_full A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response
title_fullStr A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response
title_full_unstemmed A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response
title_short A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response
title_sort case of transient existence of sars-cov-2 rna in the respiratory tract with the absence of anti-sars-cov-2 antibody response
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250069/
https://www.ncbi.nlm.nih.gov/pubmed/32470604
http://dx.doi.org/10.1016/j.ijid.2020.05.070
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