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Naturally Derived Membrane Lipids Impact Nanoparticle-Based Messenger RNA Delivery

INTRODUCTION: Lipid based nanoparticles (LNPs) are clinically successful vectors for hepatic delivery of nucleic acids. These systems are being developed for non-hepatic delivery of mRNA for the treatment of diseases like cystic fibrosis or retinal degeneration as well as infectious diseases. Locali...

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Detalles Bibliográficos
Autores principales: Kim, Jeonghwan, Jozic, Antony, Sahay, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250267/
https://www.ncbi.nlm.nih.gov/pubmed/32837581
http://dx.doi.org/10.1007/s12195-020-00619-y

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