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Arginine-Modified Polymers Facilitate Poly (Lactide-Co-Glycolide)-Based Nanoparticle Gene Delivery to Primary Human Astrocytes

PURPOSE: Astrocyte dysfunction is a hallmark of central nervous system injury or infection. As a primary contributor to neurodegeneration, astrocytes are an ideal therapeutic target to combat neurodegenerative conditions. Gene therapy has arisen as an innovative technique that provides excellent pro...

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Detalles Bibliográficos
Autores principales:	Proulx, Jessica, Joshi, Chaitanya, Vijayaraghavalu, Sivakumar, Saraswathy, Manju, Labhasetwar, Vinod, Ghorpade, Anuja, Borgmann, Kathleen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250304/ https://www.ncbi.nlm.nih.gov/pubmed/32547019 http://dx.doi.org/10.2147/IJN.S250865

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