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Gene expression regulation by the Chromodomain helicase DNA-binding protein 9 (CHD9) chromatin remodeler is dispensable for murine development

Chromodomain helicase DNA-binding (CHD) chromatin remodelers regulate transcription and DNA repair. They govern cell-fate decisions during embryonic development and are often deregulated in human pathologies. Chd1-8 show upon germline disruption pronounced, often developmental lethal phenotypes. Her...

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Detalles Bibliográficos
Autores principales: Alendar, Andrej, Lambooij, Jan-Paul, Bhaskaran, Rajith, Lancini, Cesare, Song, Ji-Ying, van Vugt, Huub, Snoek, Margriet, Berns, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250415/
https://www.ncbi.nlm.nih.gov/pubmed/32453735
http://dx.doi.org/10.1371/journal.pone.0233394