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TREM2 suppresses the proinflammatory response to facilitate PRRSV infection via PI3K/NF-κB signaling
Triggering receptor expressed on myeloid cells 2 (TREM2) serves as an anti-inflammatory receptor, negatively regulating the innate immune response. TREM2 is mainly expressed on dendritic cells and macrophages, the target cells of porcine reproductive and respiratory syndrome virus (PRRSV). Thus, we...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250469/ https://www.ncbi.nlm.nih.gov/pubmed/32401783 http://dx.doi.org/10.1371/journal.ppat.1008543 |