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TREM2 suppresses the proinflammatory response to facilitate PRRSV infection via PI3K/NF-κB signaling

Triggering receptor expressed on myeloid cells 2 (TREM2) serves as an anti-inflammatory receptor, negatively regulating the innate immune response. TREM2 is mainly expressed on dendritic cells and macrophages, the target cells of porcine reproductive and respiratory syndrome virus (PRRSV). Thus, we...

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Detalles Bibliográficos
Autores principales:	Zhu, Zhenbang, Zhang, Xiaoxiao, Dong, Wenjuan, Wang, Xiaoying, He, Sheng, Zhang, Hui, Wang, Xun, Wei, Ruiping, Chen, Yaosheng, Liu, Xiaohong, Guo, Chunhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250469/ https://www.ncbi.nlm.nih.gov/pubmed/32401783 http://dx.doi.org/10.1371/journal.ppat.1008543

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