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Dose-dependent functions of SWI/SNF BAF in permitting and inhibiting cell proliferation in vivo
SWI/SNF (switch/sucrose nonfermenting) complexes regulate transcription through chromatin remodeling and opposing gene silencing by Polycomb group (PcG) proteins. Genes encoding SWI/SNF components are critical for normal development and frequently mutated in human cancer. We characterized the in viv...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250657/ https://www.ncbi.nlm.nih.gov/pubmed/32494730 http://dx.doi.org/10.1126/sciadv.aay3823 |