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Dose-dependent functions of SWI/SNF BAF in permitting and inhibiting cell proliferation in vivo

SWI/SNF (switch/sucrose nonfermenting) complexes regulate transcription through chromatin remodeling and opposing gene silencing by Polycomb group (PcG) proteins. Genes encoding SWI/SNF components are critical for normal development and frequently mutated in human cancer. We characterized the in viv...

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Detalles Bibliográficos
Autores principales:	van der Vaart, Aniek, Godfrey, Molly, Portegijs, Vincent, van den Heuvel, Sander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250657/ https://www.ncbi.nlm.nih.gov/pubmed/32494730 http://dx.doi.org/10.1126/sciadv.aay3823

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