Inhibitory Effect of Lygodium Root on the Cytochrome P450 3A Enzyme in vitro and in vivo

PURPOSE: The aim of the present study was to investigate the interactions of the main components of Lygodium root (ie, p-coumaric acid, acacetin, apigenin, buddleoside and Diosmetin-7-O-β-D-glucopyranoside) with cytochrome P450 3A enzyme activity both in vitro and in vivo. METHODS: In vitro inhibiti...

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Detalles Bibliográficos
Autores principales: Zhou, Yunfang, Hua, Ailian, Zhou, Quan, Geng, Peiwu, Chen, Feifei, Yan, Lianhe, Wang, Shuanghu, Wen, Congcong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250706/
https://www.ncbi.nlm.nih.gov/pubmed/32546958
http://dx.doi.org/10.2147/DDDT.S249308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250706/
https://www.ncbi.nlm.nih.gov/pubmed/32546958
http://dx.doi.org/10.2147/DDDT.S249308

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