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Discovery of a new sialic acid binding region that regulates Siglec-7

Siglec-7 is a human CD33-like siglec, and is localised predominantly on human natural killer (NK) cells and monocytes. Siglec-7 is considered to function as an immunoreceptor in a sialic acid-dependent manner. However, the underlying mechanisms linking sialic acid-binding and function remain unknown...

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Detalles Bibliográficos
Autores principales:	Yamakawa, Nao, Yasuda, Yu, Yoshimura, Atsushi, Goshima, Ami, Crocker, Paul R., Vergoten, Gérard, Nishiura, Yuji, Takahashi, Takashi, Hanashima, Shinya, Matsumoto, Kana, Yamaguchi, Yoshiki, Tanaka, Hiroshi, Kitajima, Ken, Sato, Chihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250851/ https://www.ncbi.nlm.nih.gov/pubmed/32457377 http://dx.doi.org/10.1038/s41598-020-64887-4

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