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Ultra-accurate Duplex Sequencing for the assessment of pretreatment ABL1 kinase domain mutations in Ph+ ALL

Mutations of ABL1 are the dominant mechanism of relapse in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL). We performed highly accurate Duplex Sequencing of exons 4–10 of ABL1 on bone marrow or peripheral blood samples from 63 adult patients with previously untreated Ph + A...

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Detalles Bibliográficos
Autores principales:	Short, Nicholas J., Kantarjian, Hagop, Kanagal-Shamanna, Rashmi, Sasaki, Koji, Ravandi, Farhad, Cortes, Jorge, Konopleva, Marina, Issa, Ghayas C., Kornblau, Steven M., Garcia-Manero, Guillermo, Garris, Rebecca, Higgins, Jake, Pratt, Gabriel, Williams, Lindsey N., Valentine, Charles C., Rivera, Victor M., Pritchard, Justin, Salk, Jesse J., Radich, Jerald, Jabbour, Elias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250857/ https://www.ncbi.nlm.nih.gov/pubmed/32457305 http://dx.doi.org/10.1038/s41408-020-0329-y

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