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Kinesin light chain 4 as a new target for lung cancer chemoresistance via targeted inhibition of checkpoint kinases in the DNA repair network
The poor therapeutic efficacy of non-small cell lung cancer (NSCLC) is partly attributed to the acquisition of chemoresistance. To investigate the mechanism underlying this resistance, we examined the potential link between kinesin light chain 4 (KLC4), which we have previously reported to be associ...
Autores principales: | Baek, Jeong-Hwa, Yun, Hong Shik, Kim, Ju-Young, Lee, Janet, Lee, Yeon-Joo, Lee, Chang-Woo, Song, Jie-Young, Ahn, Jiyeon, Park, Jong Kuk, Kim, Jae-Sung, Lee, Kee-Ho, Kim, Eun Ho, Hwang, Sang-Gu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250887/ https://www.ncbi.nlm.nih.gov/pubmed/32457423 http://dx.doi.org/10.1038/s41419-020-2592-z |
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