Homogeneous MMR Deficiency Throughout the Entire Tumor Mass Occurs in a Subset of Colorectal Neuroendocrine Carcinomas

Neuroendocrine neoplasms comprise a heterogeneous group of tumors, categorized into neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs) depending on tumor differentiation. NECs and high-grade NETs (G3) confer a poor prognosis, demanding novel treatment strategies such as immune checkpo...

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Detalles Bibliográficos
Autores principales: Fraune, Christoph, Simon, Ronald, Hube-Magg, Claudia, Makrypidi-Fraune, Georgia, Kluth, Martina, Büscheck, Franziska, Amin, Tania, Viol, Fabrice, Fehrle, Wilfrid, Dum, David, Höflmayer, Doris, Burandt, Eike, Clauditz, Till Sebastian, Perez, Daniel, Izbicki, Jakob, Wilczak, Waldemar, Sauter, Guido, Steurer, Stefan, Schrader, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250944/
https://www.ncbi.nlm.nih.gov/pubmed/32144630
http://dx.doi.org/10.1007/s12022-020-09612-7

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