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Role of Small Intestine and Gut Microbiome in Plant-Based Oral Tolerance for Hemophilia

Fusion proteins, which consist of factor VIII or factor IX and the transmucosal carrier cholera toxin subunit B, expressed in chloroplasts and bioencapsulated within plant cells, initiate tolerogenic immune responses in the intestine when administered orally. This approach induces regulatory T cells...

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Detalles Bibliográficos
Autores principales:	Kumar, Sandeep R. P., Wang, Xiaomei, Avuthu, Nagavardhini, Bertolini, Thais B., Terhorst, Cox, Guda, Chittibabu, Daniell, Henry, Herzog, Roland W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251037/ https://www.ncbi.nlm.nih.gov/pubmed/32508814 http://dx.doi.org/10.3389/fimmu.2020.00844

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