Inhibition of TLR4 Induces M2 Microglial Polarization and Provides Neuroprotection via the NLRP3 Inflammasome in Alzheimer’s Disease

Accumulating evidence has indicated that activation of microglia and neuroinflammation reaction play a prominent role in Alzheimer’s disease (AD). Inhibition of toll-like receptor 4 (TLR4) has been shown to be associated with immune responses and brain damage, but its effects on AD remain unclear. T...

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Detalles Bibliográficos
Autores principales: Cui, Weigang, Sun, Chunli, Ma, Yuqi, Wang, Songtao, Wang, Xianwei, Zhang, Yinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251077/
https://www.ncbi.nlm.nih.gov/pubmed/32508567
http://dx.doi.org/10.3389/fnins.2020.00444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251077/
https://www.ncbi.nlm.nih.gov/pubmed/32508567
http://dx.doi.org/10.3389/fnins.2020.00444

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