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Utilizing Organoid and Air-Liquid Interface Models as a Screening Method in the Development of New Host Defense Peptides

Host defense peptides (HDPs), also known as antimicrobial peptides, are naturally occurring polypeptides (~12–50 residues) composed of cationic and hydrophobic amino acids that adopt an amphipathic conformation upon folding usually after contact with membranes. HDPs have a variety of biological acti...

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Detalles Bibliográficos
Autores principales: Choi, Ka-Yee Grace, Wu, Bing Catherine, Lee, Amy Huei-Yi, Baquir, Beverlie, Hancock, Robert E. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251080/
https://www.ncbi.nlm.nih.gov/pubmed/32509598
http://dx.doi.org/10.3389/fcimb.2020.00228

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