A new asteltoxin analog with insecticidal activity from Pochonia suchlasporia TAMA 87

A new asteltoxin analog, named asteltoxin H (1), was isolated by the solid-state fermentation of the fungus Pochonia suchlasporia var. suchlasporia TAMA 87. The chemical structure of 1 was deduced by spectroscopic methods, including 1D and 2D NMR, HRESIMS, and UV-Vis analyses. Compound 1 showed inse...

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Detalles Bibliográficos
Autores principales: Suminto, Syaefudin, Takatsuji, Eri, Iguchi, Ayako, Kanzaki, Hiroshi, Okuda, Toru, Nitoda, Teruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pesticide Science Society of Japan 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251201/
https://www.ncbi.nlm.nih.gov/pubmed/32508514
http://dx.doi.org/10.1584/jpestics.D19-081
Descripción
Sumario:A new asteltoxin analog, named asteltoxin H (1), was isolated by the solid-state fermentation of the fungus Pochonia suchlasporia var. suchlasporia TAMA 87. The chemical structure of 1 was deduced by spectroscopic methods, including 1D and 2D NMR, HRESIMS, and UV-Vis analyses. Compound 1 showed insecticidal activity against prepupae of the blowfly, Lucilia sericata, with an LD(50) value of 0.94 µg/mg prepupal body weight.

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